CODATA LOGKOW - A databank of evaluated octanol-water partition coefficients (LogP)
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Provided by:
Sangster Research Laboratories

P.O. Box 49562
CSP du Musée
5122 Cote des Neiges
Montréal, Québec, Canada
H3T 2A5

LOGKOW © is presented here for general public access by Dr. James Sangster, under the auspices of the Canadian National Committee for CODATA (CNC/CODATA).

The databank is also available as a flat file ASCII document. For more information, contact James Sangster

Partition Coefficients are useful in areas such as:

  • drug, pharmaceutical and medicinal chemistry
  • toxicology
  • environmental chemistry
  • quantitative structure-activity relationships (QSAR)
  • hydrophilic/lipophilic balance of organic compounds

The Databank contains experimental data on more than 20000 organic compounds (C1 to C130: gases, liquids and solids) including:

  • drugs and pharmaceuticals (steroidal and non-steroidal)
  • poisons and toxins
  • amino acids and peptides
  • acid-base addition compounds
  • PCBs (176 congeners) and PAHs
  • other chlorinated compounds
  • herbicides, pesticides, fungicides and insecticides
  • dyes, substituted phenols and other wastewater solutes

Other Pertinent Data included in the databank:

  • CAS Registry Numbers
  • pKa values
  • S.M.I.L.E.S. notation
  • details of measurement (see example below)
  • recommended Log KOW values
  • full bibliography in Chemical Abstracts style

Sample of LOGKOW © display output

(click on image to get a larger image)

The Databank is searchable

  1. by chemical formula
  2. by CAS Registry Number
  3. in "browse mode"

The Databank is up-to-date. Updates will be provided regularly.

Latest Databank update: 2014-06-18
For more information, contact:

Sangster Research Laboratories
Telephone: 514-340-4711, ext. 3922
Fax: 514-340-5840

CNC/CODATA Webmaster